MOTS-c
Also known as Mitochondrial ORF 12S rRNA type-c
Mitochondrial-derived peptide — A mitochondrial-derived peptide that modulates metabolic processes, with implications for exercise metabolism observed in rodent studies.
Latest released COA: 99.61%Lyophilized powder
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Specifications
| CAS number | 1627580-64-6 |
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| Molecular formula | C101H152N28O22S2 |
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| Molecular weight | 2174.62 g/mol |
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| Form | Lyophilized powder |
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Research use only. Not for human or veterinary use, consumption, diagnosis, treatment, or therapeutic purposes.
Documentation
Certificates of Analysis
Batch-specific, third-party lab certificates. Each COA is published here once its lot has been tested — preview the results, then open the full PDF.
Research context
MOTS-c research, identity and references
Also known as Mitochondrial ORF 12S rRNA type-c
What is MOTS-c?
MOTS-c is a mitochondrial-derived peptide encoded within mitochondrial 12S rRNA. Published work includes cell and animal metabolic models; those findings do not establish human safety, efficacy, or product quality.
CAS number1627580-64-6
Molecular formulaC101H152N28O22S2
Molecular weight2174.62 g/mol
SequenceMet-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
Cell and animal study
Cell and animal study
Lee C, Zeng J, Drew BG, et al. Cell Metabolism (2015).
Foundational study identifying MOTS-c and examining metabolic signaling in experimental models.
PMID 25738459 · DOI 10.1016/j.cmet.2015.02.009
Scientific review
Scientific review
Zheng Y, Wei Z, Wang T, et al. Frontiers in Endocrinology (2023).
Reviews MOTS-c biology and clearly reflects an emerging, mostly preclinical evidence base.
PMID 36761202 · DOI 10.3389/fendo.2023.1120533
Editorially curated and source-verified; not independently peer-reviewed by Astral. Last source check: 2026-08-04. How sources are selected.
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