GHK-Cu
Also known as Copper Tripeptide-1 · Gly-His-Lys Copper
Copper tripeptide — A copper-binding tripeptide (Gly-His-Lys) complexed with Cu²⁺. Investigated in fibroblast, dermal-matrix and collagen research models.
Latest released COA: 99.88%Lyophilized powder
Available vial sizes
- 50 mg$27.99In stock
- 100 mg$47.99In stock
From $27.99In stock
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Specifications
| CAS number | 89030-95-5 |
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| Molecular formula | C14H22CuN6O4 |
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| Molecular weight | 403.93 g/mol |
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| Form | Lyophilized powder |
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Research use only. Not for human or veterinary use, consumption, diagnosis, treatment, or therapeutic purposes.
Documentation
Certificates of Analysis
Batch-specific, third-party lab certificates. Each COA is published here once its lot has been tested — preview the results, then open the full PDF.
Research context
GHK-Cu research, identity and references
Also known as Copper Tripeptide-1, Gly-His-Lys Copper
What is GHK-Cu studied for?
GHK is a naturally occurring tripeptide that binds copper. The cited literature discusses cellular signaling, skin-model, and tissue-remodeling research; it does not verify the composition of a commercial vial or support human-use directions.
CAS number89030-95-5
Molecular formulaC14H22CuN6O4
Molecular weight403.93 g/mol
SequenceGly-His-Lys : Cu²⁺
Animal study
Animal study
Fu SC, Cheuk YC, Chiu WY, et al. Journal of Orthopaedic Research (2015).
A rat model with an explicitly transient result. Reported here as model evidence and its limit, not as an outcome claim.
PMID 25731775 · DOI 10.1002/jor.22831
Cell-culture study
Cell-culture study
Choi HR, Kang YA, Ryoo SJ, et al. Journal of Peptide Science (2012).
Examines copper-free GHK in a skin cell model and should not be generalized to GHK-Cu product performance.
PMID 23019153 · DOI 10.1002/psc.2455
Analytical-method review
Analytical-method review
Ogorek K, Nowak K, Wadych E, et al. Molecules (2025).
Concerns how permeation of this tripeptide is measured. Included for analytical context, which is the kind of evidence a COA speaks to.
PMID 39795193 · DOI 10.3390/molecules30010136
Literature review
Literature review
Pickart L, Vasquez-Soltero JM, Margolina A. BioMed Research International (2015).
Summarizes cellular pathways associated with GHK in skin-related research models.
PMID 26236730 · DOI 10.1155/2015/648108
Scientific review
Scientific review
Pickart L, Vasquez-Soltero JM, Margolina A Oxidative Medicine and Cellular Longevity (2012).
Reviews proposed signaling roles for the copper-binding tripeptide. A hypothesis-level review, not a demonstration of effect in people.
PMID 22666519 · DOI 10.1155/2012/324832
Editorially curated and source-verified; not independently peer-reviewed by Astral. Last source check: 2026-08-04. How sources are selected.
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