NAD+
Also known as Nicotinamide Adenine Dinucleotide · Coenzyme I · β-NAD
Redox coenzyme — A critical dinucleotide coenzyme that activates sirtuins and supports mitochondrial function, studied for cellular energy metabolism.
Latest released COA: 99.77%Lyophilized powder
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Specifications
| CAS number | 53-84-9 |
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| Molecular formula | C21H27N7O14P2 |
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| Molecular weight | 663.43 g/mol |
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| Form | Lyophilized powder |
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Research use only. Not for human or veterinary use, consumption, diagnosis, treatment, or therapeutic purposes.
Documentation
Certificates of Analysis
Batch-specific, third-party lab certificates. Each COA is published here once its lot has been tested — preview the results, then open the full PDF.
Research context
NAD+ research, identity and references
Also known as Nicotinamide Adenine Dinucleotide, Coenzyme I, β-NAD
What role does NAD+ play in laboratory research?
NAD+ is a redox coenzyme and metabolic substrate involved in many cellular processes. These broad reviews explain the biochemical context; they are not claims that adding exogenous NAD+ produces a particular human outcome.
CAS number53-84-9
Molecular formulaC21H27N7O14P2
Molecular weight663.43 g/mol
SequenceDinucleotide coenzyme (non-peptide)
Scientific review
Scientific review
Covarrubias AJ, Perrone R, Grozio A, et al. Nature Reviews Molecular Cell Biology (2021).
Reviews NAD+ metabolism and its roles in cellular processes.
PMID 33353981 · DOI 10.1038/s41580-020-00313-x
Scientific review
Imai S, Guarente L. Trends in Cell Biology (2014).
Explains the biochemical relationship between NAD+ availability and sirtuin activity.
PMID 24786309 · DOI 10.1016/j.tcb.2014.04.002
Scientific review
Verdin E Science (2015).
A widely cited overview of NAD+ biology. Establishes why the cofactor is studied; it says nothing about any supplied material.
PMID 26785480 · DOI 10.1126/science.aac4854
Scientific review
Chini CCS, Cordeiro HS, Tran NLK, et al. Aging Cell (2024).
A recent synthesis of senescence-related NAD metabolism, included to keep the reading list current rather than to support a use.
PMID 37424179 · DOI 10.1111/acel.13920
Scientific review
Xie N, Zhang L, Gao W, et al. Signal Transduction and Targeted Therapy (2020).
Reviews mechanisms and states where therapeutic potential remains unproven. Cited for that boundary.
PMID 33028824 · DOI 10.1038/s41392-020-00311-7
Editorially curated and source-verified; not independently peer-reviewed by Astral. Last source check: 2026-08-04. How sources are selected.
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